I bought a kit for a baby blanket that had minky, flannel and cotton in it. It was to be cut into squares and sewn into block borders to go around the flannel center panel of flannel, alternating the minky, cotton and flannel squares. Also the cotton was to go around the flannel center panel as a border. The back was flannel and no batting used. I didn't have a problem sewing it together but haven't washed it yet. If different materials come in a kit I don't see why you can't put your own together.

I have used Minke and flannel in a baby quilt with good results.

I have mixed flannel and cotton but not fleece, but if they all wash the same why not. I did not have any trouble at all washing the flannel and cotton together.

What knlsmith said! Prewashing in hot water and machine drying is a MUST if you are going to mix cottons with blends or non-cottons such as fleece. Cotton will always shrink some, blends such as poly-cotton will shrink a little, and poly fabrics including fleece will not shrink. Your quilt will end up really wonky the first time it's washed if you do not prewash before you start cutting blocks.

I'm sure any small child will love a quilt with the different textures so go for it!

I did four scrappy memory quilts from outgrown childrens clothing and used knits, cotton,pajamas, flannel, fleece and even cordory and they did up great. Two of the quilts were from boys clothing and two were from girls clothing including her dresses.

I bet it would be a fun quilt, but I think I would use a piece of muslin for foundation

I'm going to make rag quilts have flannel washed dried and cut, will wash the denim and dry, do I need to wash the regular quilting cotton also? will not be using batting, and cutting squares 8"sq allowing for 3/4" seams to rag out.

You said it, I agree with what you said 100%

I wouldn't have a problem using cotton and flannel in a quilt, however, I would be sure to wash the flannel in hot water, as it really tends to shrink a lot, but then I pre-wash 99% of my fabrics anyway.

Personally, I don't see a problem with mixing cotton flannel and cotton quilting fabric if you pre-washed. Stretchy fabric makes me nervous in any quilt unless you stabilize it first.